Autologous Biologics in Orthopedics: A Closer Look at PRP and Stem Cell Injections

Orthobiologics, including PRP and stem cell injections, have gained popularity in orthopedic surgery as potential treatments for a variety of conditions. While these injections hold promise, there is still much debate and uncertainty surrounding their effectiveness and appropriate use. PRP injections involve drawing blood from the patient and separating the plasma and platelets, which are then reinjected into the target tissues. Stem cell injections, on the other hand, utilize bone marrow or adipose tissue-derived cells with the potential to differentiate into different types of tissues. Despite their popularity, the scientific consensus on when and how to use orthobiologics remains unclear, with conflicting research and varying opinions. The FDA has strict regulations regarding their use, including limitations on cell manipulation and requiring the injections to be performed in the same setting. It is important for patients to have informed discussions with their healthcare providers to fully understand the potential benefits and limitations of orthobiologic treatments.